The incretin system is the set of gut-derived hormone pathways that modulate insulin secretion in response to nutrient intake. Its two principal receptors, GLP-1R…
Read the full description →Retatrutide
Synthetic 39-residue peptide; agonist at the GLP-1, GIP and glucagon receptors. Supplied for in vitro receptor-signalling and metabolic-pathway research.
Also searched as LY3437943 · GLP-1 / GIP / glucagon triple agonist · reta
At a glance
Retatrutide is triple agonist · GLP-1 / GIP / glucagon receptors.
- Supplied as
- Lyophilized (freeze-dried) powder in a sealed vial
- Vial sizes
- 15 mg · 30 mg
- Purity
- HPLC-verified, 99% or higher
- Current batch
- RET-26031501, issued March 15, 2026
- Certificate of analysis
- Published in full for this batch
- Ships
- From Texas to all 50 US states
- Intended use
- Laboratory research only. Not for human or veterinary use.
Chemical data
Handling & verification
A synthetic 39-residue peptide acting as an agonist at three receptors at once — GLP-1, GIP and glucagon. Supplied for in vitro receptor-signalling and metabolic-pathway research, where that triple activity is the point of interest.
Presentation and storage
Supplied lyophilized in a sealed vial under vacuum. Store the sealed vial at −20 °C for long-term storage; refrigeration at 2–8 °C is adequate over shorter periods. Keep away from light and moisture.
Allow the vial to reach room temperature before opening, so atmospheric moisture does not condense onto the powder.
Reconstitution
Reconstitute with bacteriostatic water. Direct the diluent down the inside wall of the vial rather than onto the powder, and swirl gently — do not shake, as agitation can denature the peptide.
- 10 mg vial in 2 mL diluent gives a 5 mg/mL stock
- 15 mg vial in 3 mL diluent gives a 5 mg/mL stock
- 30 mg vial in 3 mL diluent gives a 10 mg/mL stock
Once reconstituted, store at 2–8 °C and protect from light. Avoid repeated freeze-thaw cycles — aliquot the stock if it will be drawn on more than a few times.
Verification
Every lot is assayed by HPLC and released at ≥99% purity. The certificate of analysis for the batch currently shipping (RET-26031501, released 15 March 2026) is linked above and states the batch number, the assay method and the measured purity.
Common questions
Does Retatrutide come with a certificate of analysis?
Yes. Every lot of Retatrutide ships with its own certificate of analysis showing HPLC purity, and the current certificate is published on our COA page before you buy — you do not have to order first or email anyone to see it.
What purity is Retatrutide?
HPLC-verified at 99% or higher. The certificate for each lot states the measured figure, the detection wavelength and the method used, so the number can be checked rather than taken on trust.
How is Retatrutide supplied and where does it ship?
It is supplied as lyophilized (freeze-dried) powder in a sealed vial, protected against light and impact. Full US shipping, operating from Texas. Delivery estimates are provided by the carrier at checkout.
How should Retatrutide be stored?
Keep the lyophilized vial cold and dark — refrigerated for near-term use, frozen for longer storage. Once reconstituted it belongs in the refrigerator and its usable life is measured in weeks rather than months. Aliquot rather than thawing the same vial repeatedly, because freeze-thaw cycles cost more stability than most people expect.
How do I reconstitute Retatrutide?
Add bacteriostatic water slowly down the inner wall of the vial so the stream does not strike the powder directly, then let it dissolve on its own — swirl gently if needed, never shake. The volume you add sets the concentration, so decide the concentration first and work backwards. Our free reconstitution calculator does that arithmetic and gives the volume to draw per aliquot.
Is Retatrutide for human use?
No. Retatrutide is supplied strictly as a reference material for laboratory research use only. It is not a drug, food, cosmetic or medical device, it is not for human or veterinary consumption, and it is not intended to diagnose, treat, cure or prevent any disease. We do not provide dosing guidance or protocols of any kind.
See the certificate · Reconstitution calculator · All questions
Handling guides
Other compounds
For laboratory and research use only. Not for human or veterinary use, diagnosis, or consumption. Products are sold to qualified researchers and are not drugs, foods, or cosmetics.