Incretin System
The incretin system is the set of gut-derived hormone pathways that modulate insulin secretion in response to nutrient intake. Its two principal receptors, GLP-1R and GIPR, are class B G-protein-coupled receptors, and the glucagon receptor (GCGR) sits alongside them in the same family. Research interest in this class has moved from single-receptor agonists toward peptides engineered to engage two or three of these receptors at once, because the signalling consequences of combined activation are not simply the sum of the parts.
Compounds here are grouped by the receptor system they act on, not by structure.
Laboratory research use only. Not for human or veterinary use.
DetailAbout this one
What sets this apart from the neighbouring classes.
- Retatrutide 15 mg / 30 mg
The only compound in this class. A 39-residue peptide engaging three receptors at once — GLP-1, GIP and glucagon — which is what separates it from the single- and dual-agonist literature that preceded it.
Certificate of analysis →
Handling: reconstitution storage and stability checking a certificate is genuine
