Melanocortin System
The melanocortin system comprises five G-protein-coupled receptors, MC1R through MC5R, with distinct tissue distributions and downstream effects. Most synthetic ligands studied in this space are non-selective across MC1R, MC3R and MC4R, which makes receptor-subtype discrimination a central problem in the literature rather than a solved one.
Compounds here are grouped by the receptor family they act on, not by structure.
Laboratory research use only. Not for human or veterinary use.
CompareChoosing between these
What separates each of these from the others in the class.
- Melanotan-2 10 mg
Non-selective across MC1R, MC3R and MC4R, so it engages the pigmentation receptor alongside the central ones.
Certificate of analysis → - PT-141 10 mg
The active metabolite of melanotan II, with activity concentrated at MC3R and MC4R rather than MC1R. That narrower subtype coverage is exactly why the two are usually studied as a pair.
Certificate of analysis →
Handling: reconstitution storage and stability checking a certificate is genuine
