Catalog  /  Melanocortin System  /  PT-141
PT-141 · 10 mg PT-141
HPLC ≥99%
Per-lot COA
Sealed vial
Compound class Melanocortin System

Also grouped under Neuropeptides.

The melanocortin system comprises five G-protein-coupled receptors, MC1R through MC5R, with distinct tissue distributions and downstream effects. Most synthetic…

Read the full description and all 2 compounds →

PT-141 NewMelanocortin SystemNeuropeptides

Cyclic heptapeptide lactam (bremelanotide); active metabolite of melanotan II and a non-selective melanocortin-receptor agonist with principal activity at MC3R and MC4R. Supplied for receptor-pharmacology research.

Also searched as bremelanotide · PT141

$44.99USD
10 mg vial · lyophilized · reconstitute before use
Select size
In stock · ships from Texas
Discreet packaging Lyophilized · sealed vial Batch-tested
Full US shipping · operating from Texas

At a glance

PT-141 is cyclic heptapeptide lactam · non-selective melanocortin receptor agonist.

Supplied as
Lyophilized (freeze-dried) powder in a sealed vial
Vial sizes
10 mg
Purity
HPLC-verified, 99% or higher
Current batch
800028-26031301, issued March 13, 2026
Certificate of analysis
Published in full for this batch
Ships
From Texas to all 50 US states
Intended use
Laboratory research only. Not for human or veterinary use.
View the certificate for batch 800028-26031301

Chemical data

PT-141
Cyclic heptapeptide lactam · non-selective melanocortin receptor agonist
CAS189691-06-3
SynonymBremelanotide
Mol. formulaC₅₀H₆₈N₁₄O₁₀
Mol. weight1 025.2 g/mol
SequenceAc-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Structure7 residues · lactam bridge Asp²→Lys⁷
FormLyophilized · 3 mL vial
Purity≥99% HPLC verified
Storage2–8°C · light-protected
SolubilityReconstitute with bacteriostatic water

Handling & verification

PT-141 (bremelanotide) is a cyclic heptapeptide analogue of α-melanocyte-stimulating hormone, and a metabolite of the earlier compound melanotan-II. It is supplied as a reference compound for in vitro work on melanocortin receptor signalling, and ships as a white lyophilized powder, HPLC-verified at ≥99% purity.

Presentation and storage

Supplied lyophilized in a sealed vial. Store the sealed vial at −20 °C for long-term storage; refrigeration at 2–8 °C is adequate over shorter periods. Keep away from light and moisture.

Allow the vial to reach room temperature before opening, so atmospheric moisture does not condense onto the cake.

Reconstitution

Reconstitute with bacteriostatic water. Direct the stream down the inside wall of the vial rather than onto the cake, then let it stand and swirl gently — do not shake, as agitation can denature the peptide.

  • 10 mg vial in 1 mL diluent gives a 10 mg/mL stock
  • 10 mg vial in 2 mL diluent gives a 5 mg/mL stock
  • 10 mg vial in 5 mL diluent gives a 2 mg/mL stock

Once reconstituted, store at 2–8 °C and protect from light. Avoid repeated freeze-thaw cycles — aliquot the stock if it will be drawn on more than a few times. Our reconstitution calculator works out any other combination.

Verification

Every lot is assayed by HPLC and released at ≥99% purity, and a per-lot certificate of analysis is available stating the batch number, the assay method and the measured purity. If you would like the certificate for the batch currently shipping before ordering, ask and we will send it.

Common questions

Does PT-141 come with a certificate of analysis?

Yes. Every lot of PT-141 ships with its own certificate of analysis showing HPLC purity, and the current certificate is published on our COA page before you buy — you do not have to order first or email anyone to see it.

What purity is PT-141?

HPLC-verified at 99% or higher. The certificate for each lot states the measured figure, the detection wavelength and the method used, so the number can be checked rather than taken on trust.

How is PT-141 supplied and where does it ship?

It is supplied as lyophilized (freeze-dried) powder in a sealed vial, protected against light and impact. Full US shipping, operating from Texas. Delivery estimates are provided by the carrier at checkout.

How should PT-141 be stored?

Keep the lyophilized vial cold and dark — refrigerated for near-term use, frozen for longer storage. Once reconstituted it belongs in the refrigerator and its usable life is measured in weeks rather than months. Aliquot rather than thawing the same vial repeatedly, because freeze-thaw cycles cost more stability than most people expect.

How do I reconstitute PT-141?

Add bacteriostatic water slowly down the inner wall of the vial so the stream does not strike the powder directly, then let it dissolve on its own — swirl gently if needed, never shake. The volume you add sets the concentration, so decide the concentration first and work backwards. Our free reconstitution calculator does that arithmetic and gives the volume to draw per aliquot.

Is PT-141 for human use?

No. PT-141 is supplied strictly as a reference material for laboratory research use only. It is not a drug, food, cosmetic or medical device, it is not for human or veterinary consumption, and it is not intended to diagnose, treat, cure or prevent any disease. We do not provide dosing guidance or protocols of any kind.

See the certificate · Reconstitution calculator · All questions

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For laboratory and research use only. Not for human or veterinary use, diagnosis, or consumption. Products are sold to qualified researchers and are not drugs, foods, or cosmetics.